2016, Cilt 25, Sayı 0, Sayfa(lar) 092-094
Oxalate Nephropathy Secondary to Chronic Pancreatitis: Case Report
DOI 10.5262/tndt.2016.19
Nergiz BAYRAKCI1, Nihal ÖZKAYAR1, Aysel ÇOLAK2, Müge EREK ERSÖZEN1, Ebru GÖK OĞUZ3, Fatih DEDE1
1Ankara Numune Eğitim ve Araştırma Hastanesi, Nefroloji Bölümü, Ankara, Türkiye
2Ankara Numune Eğitim ve Araştırma Hastanesi, Patoloji Bölümü, Ankara, Türkiye
3Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Nefroloji Bölümü, Ankara, Türkiye
Keywords: Acute kidney injury, Oxalate nephropathy, Chronic pancreatitis, Diabetes mellitus

Chronic pancreatitis is a rare cause of oxalate nephropathy. The aim of this case report was to present a patient hospitalized with acute kidney injury who was diagnosed with oxalate nephropathy and concurrent chronic pancreatitis on further investigation.

A 48-year-old diabetic male patient was hospitalized with the diagnosis of acute kidney injury. Renal biopsy was performed. Biopsy findings were in favor of oxalosis and acute tubular necrosis. A careful medical history revealed alcohol abuse, episodic epigastric pain, chronic diarrhea and weight loss. After detecting signs of chronic pancreatitis and a cyctic lesion on abdominal computed tomography images, he underwent surgery for suspected malignancy. Histological findings were suggestive of chronic pancreatitis. The patient was diagnosed with secondary hyperoxaluria and oxalate nephropathy associated with chronic pancreatitis and was discharged on hemodialysis.

Although secondary hyeroxaluria and DM are among known complications of chronic pancreatitis, the coexistence of these two disorders in the same patient is a rare entity. There is no consensus about renal biopsy indications in type 2 diabetes mellitus patients. Medical history and clinical features are particularly important in terms of the renal biopsy decision in these patients, as in our case.


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