2016, Cilt 25, Sayı 0, Sayfa(lar) 071-074
Case Report: Scleroderma Renal Crisis Presenting as Thrombotic Microangiopathy
DOI 10.5262/tndt.2016.12
Mehmet Can UĞUR1, Ferhat EKİNCİ1, Tuğba KARADENİZ2, Elif GRAM1, Hülya ÇOLAK3, Cengiz CEYLAN4, Harun AKAR1
1İzmir Tepecik Education and Research Hospital, Department of Internal Medicine, İzmir, Turkey
2İzmir Tepecik Education and Research Hospital, Department of Pathology, İzmir, Turkey
3İzmir Tepecik Education and Research Hospital, Department of Nephrology, İzmir, Turkey
4İzmir Tepecik Education and Research Hospital, Department of Hematology, İzmir, Turkey
Keywords: Scleroderma, Renal crisis, Thrombotic microangiopathy, Hemodialysis

Scleroderma is a systemic autoimmune disease of unknown origin characterized by excessive deposition of collagen and other connective tissue macromolecules in multiple organs. It can cause thrombotic microangiopathy. Scleroderma renal crisis is a major complication of this disorder. We aimed to present a case that presented with thrombotic microangiopathy findings and was diagnosed as scleroderma renal crisis.

A 56-year-old female patient presented with hypertension and thrombotic microangiopathy signs. After examination and renal biopsy, scleroderma renal crisis with thrombotic microangiopathy was diagnosed. A routine hemodialysis program and an angiotensin converting enzyme inhibitor was started

Scleroderma renal crisis should be kept in mind in patients presenting with malignant hypertension and thrombotic microangiopathy.


Türk Nefroloji Derneği'nin yayın organıdır.