2018, Cilt 27, Sayı 2, Sayfa(lar) 221-224
Hypercalcemia and Acute Kidney Injury Due to Oral Vitamin D Replacement
DOI 10.5262/tndt.2018.2827
İlter BOZACI1, Tugay AVCI2, Sevil NALBANT2, İbrahim VASI2, Mehmet SOYDAN1
1Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Nefroloji Bilim Dalı, Eskişehir, Türkiye
2Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Eskişehir, Türkiye
Keywords: Vitamine D, Hypercalcemia, Acute kidney injury

Vitamin D (calciferol), is a fat-soluble vitamin and it is contained in very few foods. The main source of this vitamin is skin production. Subclinical vitamin D deficiency, diagnosed by a low 25 hydroxy vitamin D level, is a very common disorder. The first step in the evaluation of a patient with hypercalcemia is to verify the condition with a repeat measurement. After that, differential diagnosis of parathormone (PTH) mediated and non PTH mediated hypercalcemia should be performed by the measurement of PTH. A 71-year-old female patient presented to the hospital with a history of nausea, loss of appetite, and confusion for 1 week. Hypercalcemia and acute kidney injury, linked to oral vitamin D replacement, were detected. Vitamin D has many important effects on various systems and paying attention to the total replacement dosage is as important as treating the deficiency itself.

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