2018, Cilt 27, Sayı 3, Sayfa(lar) 327-330
Bilateral Renal Infarction due to MTHFR C677T Mutation and Hyperhomocysteinemia
DOI 10.5262/tndt.2018.2971
Fatma Betül GÜZEL1, Egemen ŞENEL1, Fatih ÖCAL2, Betül KIZILDAĞ3, Ertuğrul ERKEN1, Orçun ALTUNÖREN1, Özkan GÜNGÖR1
1Kahramanmaraş Sütçü İmam Üniversitesi, Tıp Fakültesi, Nefroloji Bilim Dalı, Kahramanmaraş, Türkiye
2Kahramanmaraş Sütçü İmam Üniversitesi, Tıp Fakültesi, Hematoloji Anabilim Dalı, Kahramanmaraş, Türkiye
3Kahramanmaraş Sütçü İmam Üniversitesi, Tıp Fakültesi, Radyoloji Anabilim Dalı, Kahramanmaraş, Türkiye
Keywords: Renal infarct, Homocysteine, MTHFR C677

Renal infarction is a condition induced by renal artery occlusion and causes renal parenchymal damage. The most common cause of renal infarction is atheroembolic cardiac diseases. Other causes are trauma, autoimmune diseases and hypercoagulability. Homocysteine is a vasculotoxic substance, and mutations in the Methyltetrahyrofolate Reductase (MTHFR) enzyme may result in an increase in serum homocysteine levels. In this report, we present a 35-year-old case with bilateral renal infarction, for which we hold the MTHFR C677T mutation and hyperhomocysteinemia responsible, because of its rarity.

Türk Nefroloji Derneği'nin yayın organıdır.